Padres Pedal the Cause Awards $2.4 Million in Funding for Cancer Research

11 new collaborative cancer research projects receive Padres Pedal the Cause Discovery Grants

 

Padres Pedal the Cause announced the first wave of cancer research teams that will receive funding through its annual Discovery Grant program. The non-profit organization awards millions of dollars each year to cross-institutional teams of physicians and scientists from San Diego’s best cancer institutions including Moores Cancer Center at UC San Diego Health, Salk Institute for Biological Studies, Sanford Burnham Prebys Medical Discovery Institute and Rady Children’s Hospital—San Diego.  The Discovery Grant selection is highly competitive.  Proposals are strongly encouraged to include collaborative study between at least two of the beneficiary organizations and are screened through a rigorous vetting process.  Funding is awarded to best-in-class project submissions to greenlight project exploration with the hope that initial findings may lead to additional funding from national sources, and ultimately a cure.

 

“The Padres Pedal the Cause Discovery Grants are opening the door to critically needed research,” says doctors Frank Furnari and Geoffrey Wahl, recipients of a 2018 Discovery Grant. “This funding has allowed us to build a highly collaborative research team to tackle glioblastoma, a particularly aggressive brain cancer.  Working with team members Jorge Benitez and Leo Li, we aim to target a specific gene mutation that may be translated to the clinic for treatment of this deadly cancer.”

 

To date, “Padres Pedal” has raised and donated over $7.1 million to fund 42 translational research projects for all types of cancers including pancreatic, breast, brain, pediatric, skin, lung, colorectal, gastrointestinal, ovarian and endometrial.  100% of this funding stays local to advance cancer research and treatment in San Diego, which is quickly becoming a national hub for cancer study due to its unique cluster of NCI-designated cancer centers, biotech industry and life sciences community.

 

“We are in a historic time of progress for cancer research,” says Executive Director of Padres Pedal the Cause, Anne Marbarger.  “The advancements in technologies and methods of cancer treatment, many of which are being pioneered by doctors and researchers here in San Diego, give us hope for a future where cancer is understood, managed and hopefully, cured.  Padres Pedal is proud to support these scientists in leading the fight against cancer. We hope the whole community will join us in doing so this November.”

 

Padres Pedal the Cause holds one of the largest stand-alone cancer fundraising events in San Diego.  Each year in November, thousands of participants, survivors, teams, sponsors and volunteers gather at Petco Park to raise money for cancer research and move closer to a cure.  The organization works hard to underwrite all operational and event costs through partnerships with corporate sponsors, in turn allowing every participant dollar raised to fund life-saving cancer research.  The community is looking forward to the 2018 event which will be held on Saturday, November 17 at Petco Park.

 

Congratulations to the 23 principal investigators and their teams that are leading San Diego’s fight against cancer.  The 2018 Padres Pedal the Cause Discovery Grant recipients are:

 

“Inducing Cytosolic Chromatin Fragments in Cancer Cells to Turn Cold Tumors Hot”
Jack Bui, Moores Cancer Center
Peter Adams, Sanford Burnham Prebys Medical Discovery Institute

 

“Understanding and Targeting NRF2 in Pancreatic Cancer”
Michael Karin, Moores Cancer Center
Andrew Lowy, Moores Cancer Center
Jorge Moscat, Sanford Burnham Prebys Medical Discovery Institute

 

“Targeting a Therapeutic Vulnerability in PTEN-Deficient Brain Tumors”
Frank Furnari, Moores Cancer Center
Geoff Wahl, Salk Institute for Biological Studies

 

“Natural Killer Cells for Treatment of Medulloblastoma”
Dan S. Kaufman, Moores Cancer Center
Robert J. Wechsler-Reya, Sanford Burnham Prebys Medical Discovery Institute

 

“Transcriptomic and Epigenomic Profiling to Reveal Tumor-Infiltrating Lymphocyte and Microglia Functional Phenotype and Clonality In Pediatric Brain Tumors”
Anusha Preethi Ganesan, Rady Children’s Hospital, San Diego
P. Vijayanand, La Jolla Institute

 

“Responses of Melanoma Patients to Checkpoint Immunotherapy”
Linda Bradley, Sanford Burnham Prebys Medical Discovery Institute
Gregory Daniels, Moores Cancer Center

 

“Enhanced Breast Cancer Risk Prediction from Imputed Gene Expression”
Hannah Carter, Moores Cancer Center
Graham McVicker, Salk Institute for Biological Studies

 

“Epigenetic Profiling of Endometrial Cancer”
Diana Hargreaves, Salk Institute for Biological Studies
Ramez Eskander, Moores Cancer Center

 

“Targeting Fibroblast Heterogeneity to Improve Surgical Outcomes in Pancreatic Cancer”
Ronald M. Evans, Salk Institute for Biological Studies
Michael Bouvet, Moores Cancer Center

 

“A Novel Role for Histidine Kinase Activity in Neuroblastoma Pathogenesis”
Peter Zage, Rady Children’s Hospital, San Diego
Tony Hunter, Salk Institute for Biological Studies

 

“Development and Implementation of a Peer-Navigation Intervention to Improve Research Literacy in Pediatric Cancer Trials”
Paula Aristizabal, Rady Children’s Hospital, San Diego
Elena Martinez, UC San Diego Health

 

A detailed description of these cancer research projects, and all 42 of the funded Padres Pedal Discovery Grants, is available on our Impact page.

 


About Padres Pedal the Cause

Padres Pedal the Cause is a 501(c)(3) non-profit organization dedicated to funding collaborative cancer research in San Diego. To date, Padres Pedal has raised and donated over $7.1 million to fund 42 translational research projects at Moores Cancer Center at UC San Diego Health, the Salk Institute for Biological Studies, Rady Children’s Hospital and Sanford-Burnham Prebys Medical Discovery Institute. It is our goal that the research funded by Padres Pedal the Cause will lead to increased survivorship and ultimately, a cure. For more information or to register for the November 17 event, please visit gopedal.org. Padres Pedal can also be found on Facebook, Twitter and Instagram.

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